cellexusinc

Differentiation of Human Pluripotent Stem Cells Into Definitive Endoderm Cells in Various Flexible Three-Dimensional Cell Culture Systems: Possibilities and Limitations

The era of human stem cell-derived spheroids and organoids represents a serious step in fixing quite a few medical, pharmacological, and organic challenges. Because of the benefits of three-dimensional (3D) cell tradition programs and the varied functions of human pluripotent stem cell (iPSC)-derived definitive endoderm (DE), we studied the affect of spheroid dimension and 3D…

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cellexusinc

3D microgroove electrical impedance sensing to examine 3D cell cultures for antineoplastic drug assessment

In latest a long time, three-dimensional (3D) most cancers cell fashions have attracted growing curiosity within the area of drug screening attributable to their vital benefits in additional correct simulations of heterogeneous tumor conduct in vivo in comparison with two-dimensional fashions. Moreover, drug sensitivity testing primarily based on 3D most cancers cell fashions can present…

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cellexusinc

A digital microfluidic system with 3D microstructures for single-cell culture

Regardless of the exact controllability of droplet samples in digital microfluidic (DMF) methods, their functionality in isolating single cells for long-time tradition remains to be restricted: usually, just a few cells could be captured on an electrode. Though fabricating small-sized hydrophilic micropatches on an electrode aids single-cell seize, the actuation voltage for droplet transportation needs…

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Magnetic properties of nanoparticles as a function of their spatial distribution on liposomes and cells.

Magnetic properties of nanoparticles as a function of their spatial distribution on liposomes and cells.

The aggregation processes of magnetic nanoparticles in biosystems are analysed by evaluating the magnetic properties of three programs with totally different spatial distributions of the nanoparticles. The primary one is iron oxide nanoparticles (NPs) of 14 nm synthesized by coprecipitation with two coatings, (3-aminopropyl)trimethoxysilane (APS) and dimercaptosuccinic acid (DMSA). The second is liposomes with encapsulated nanoparticles, which…

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First Report of Leaf Spot Caused by Phoma costarricensis on Delphinium malabaricum in Western Ghats of India.

First Report of Leaf Spot Caused by Phoma costarricensis on Delphinium malabaricum in Western Ghats of India.

Delphinium L. is a genus of greater than 300 species of perennial flowering crops belonging to the household Ranunculaceae and is native all through the Northern Hemisphere. In India, 24 species are discovered primarily within the Himalayan areas. Delphinium malabaricum (Huth) Munz is the one species of the genus endemic to northern Western Ghats. Its…

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The MAPHEUS module CellFix for studying the influence of altered gravity on the physiology of single cells.

The MAPHEUS module CellFix for studying the influence of altered gravity on the physiology of single cells.

Gravity is the one fixed stimulus in the course of the evolution of life. To research the impression of the absence of gravity on dwelling programs, their molecular and morphological standing needs to be studied beneath microgravity situations. The experiment unit CellFix was developed with a view to present the potential of publicity and chemical…

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Modeling inherited physiological structures based on hyperbolic numbers

Modeling inherited physiological structures based on hyperbolic numbers

The article is dedicated to utilizing the arithmetic of multi-dimensional hyperbolic numbers and their matrix representations for modeling of various inherited biosystems, that are elements of the holistic physique. The listing of thought of fashions contains phyllotaxis sequences; Punnet squares of the Mendelian genetics; the principle psychophysical Weber-Fechner regulation, and a few others. This modeling method…

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