Tag: phi29 lucigen
Production of Human Acid-Alpha Glucosidase With a Paucimannose Structure by Glycoengineered Arabidopsis Cell Culture
Plant cell cultures have emerged as a promising platform for the manufacturing of biopharmaceutics resulting from their cost-effectiveness, security, skill to regulate the cultivation, and secrete merchandise into tradition medium. Nevertheless, the usage of this platform is hindered by the era of plant-specific N-glycans, the lack to supply important N-glycans for mobile supply of biopharmaceutics, and low…
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A Scalable Method to Study Neuronal Survival in Primary Neuronal Culture with Single-cell and Real-Time Resolution
Neuronal loss is on the core of many neuropathologies, together with stroke, Alzheimer’s illness, and Parkinson’s illness. Totally different strategies had been developed to review the method of neuronal survival upon cytotoxic stress. Most strategies are based mostly on biochemical approaches that don’t enable single-cell decision or contain advanced and expensive methodologies. Introduced here’s a…
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Optimization of muscle cell culture media using nonlinear design of experiments
Optimizing media for organic processes, equivalent to these utilized in tissue engineering and cultivated meat manufacturing, is tough as a result of intensive experimentation required, variety of media parts, nonlinear and interactive responses, and the variety of conflicting design goals. Right here we exhibit the capability of a nonlinear design-of-experiments (DOE) technique to foretell optimum…
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Development of a Pig Mammary Epithelial Cell Culture Model as a Non-Clinical Tool for Studying Epithelial Barrier-A Contribution from the IMI-ConcePTION Project
The ConcePTION mission goals at producing additional information in regards to the dangers associated to the usage of treatment throughout breastfeeding, as this data is missing for mostly used medication. Taking into account a number of points, the pig mannequin has been thought of by the consortium as essentially the most applicable selection. The current…
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