The use of COLD-PCR, DHPLC and GeneScanning for the highly sensitive detection of c-KIT somatic mutations in canine mast cell tumours.

• Robert Brown

The traditional polymerase chain response (PCR)/sequencing strategies could also be poorly fitted to the detection of somatic mutations in canine mast cell tumour (MCT) samples owing to restricted sensitivity. This examine was geared toward establishing novel and extra delicate strategies, assessing their restrict of detection and evaluating their sensitivity with standard strategies.Two completely different ‘driver’…