Detection of mutations in gyrB using denaturing high performance liquid chromatography (DHPLC) among Salmonella enterica serovar Typhi and Paratyphi A.

Fluoroquinolone resistance is mediated by mutations within the quinolone-resistance figuring out area (QRDR) of the topoisomerase genes. Denaturing excessive efficiency liquid chromatography (DHPLC) was evaluated for detection of clinically essential mutations in gyrB amongst Salmonella. Salmonella Typhi and S. Paratyphi A characterised for mutation in QRDR of gyrA, parC and parE had been studied for…

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